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Updated: Sep 17, 2025

Ubiquitin Chain Analysis by Parallel Reaction Monitoring
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Ubiquitin Chain Analysis by Parallel Reaction Monitoring

Published on: June 17, 2020

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在细胞中使用协同存在的ubiquitin结合实体来解链特定的ubiquitination

Muhammad Shahzad Ali1, Christopher Rainville1, Janelle Pedroza2

  • 1Progenra Inc, 271A Great Valley Parkway, Malvern, PA, 19335, USA.

Scientific reports
|July 2, 2025
PubMed
概括

这项研究引入了链选择性并列乌比基因结合实体 (TUBE),用于对蛋白质乌比基因化结合类型的高通量评估. 该方法成功地区分了RIPK2的K48和K63无处不在,推动了向蛋白质降解研究.

关键词:
E3 连接酶的使用.分子粘合剂是分子粘合剂.这就是 PROTACs.蛋白质酶体是一种蛋白质酶体.管道 管道 管道乌比奎丁结合域的域名.

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