评估COVID-19疫苗接种后流产发生率
Fariba Shahraki-Sanavi1, Sajad Sahab-Negah2, Sairan Nili3
1Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Scientific reports
|July 2, 2025
概括
怀孕期间用Sinopharm,Sputnik V,AZD1222和Barekat疫苗接种COVID-19疫苗并没有增加流产的风险. 这项研究发现,不同类型的疫苗中流产率没有统计学上显著的差异,这表明它们的安全性.
科学领域:
- 生殖健康 生殖健康
- 疫苗学 疫苗学 疫苗学
- 传染病流行病学 传染病流行病学
背景情况:
- 在COVID-19感染期间怀孕可能会导致母亲的不良结果.
- 了解怀孕期间COVID-19疫苗的安全性对于公共卫生至关重要.
研究的目的:
- 评估COVID-19疫苗接种对流产风险的影响.
- 在孕妇中评估特定的COVID-19疫苗 (Sinopharm,Sputnik V,AZD1222,Barekat) 的安全性.
主要方法:
- 一项包括26701名在2021年4月至2022年8月期间在伊朗接种疫苗的生育年龄女性 (15-49岁) 的队列研究.
- 分析的重点是459名孕妇,直到怀孕完成后才跟踪.
- 计算了流产发病率,并对不同类型的疫苗进行了比较.
主要成果:
- 在459名孕妇中,共记录了50例流产.
- 总体而言,流产的累计发病率为10.9%,分别为AZD1222,Sputnik V,Sinopharm和Barekat疫苗的发病率为11.0%,9.7%,12.0%和11.1%.
- 疫苗组之间没有观察到流产发生率的统计学上显著差异 (P值 = 0.962).
结论:
- 用Sputnik V,Sinopharm,Barekat和AZD1222接种COVID-19疫苗似乎不会增加流产的可能性.
- 研究的COVID-19疫苗证明了关于孕妇流产风险的安全性.
- 研究结果支持在孕妇群体中继续使用这些疫苗.
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