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相对脂肪量与女性不孕症的关联:基于NHANES 2017-2020年的横截面研究

Qian Tang^1,2, Qiang Zhang², Rui Xia²

¹Reproductive Centre, The 940th Hospital of the Joint Logistic Support Force of PLA, Lanzhou, 730050, China.

Scientific reports

|July 2, 2025

概括

较高的相对脂肪量 (RFM),一种内脏脂肪的测量,与女性不孕症风险的增加有关. 这一发现表明,RFM可以帮助进行不孕症查.

科学领域:

生殖健康生殖健康
身体组成分析身体成分分析
流行病学流行病学

背景情况:

相对脂肪量 (RFM) 是一种新兴的体脂测量指数,可以更好地了解内脏脂肪的分布.
了解影响女性不孕症的因素对于生殖健康至关重要.
现有的身体成分指标可能无法完全捕捉与内脏脂肪积累相关的风险.

研究的目的:

调查相对脂肪量 (RFM) 和女性不孕症之间的关联.
确定RFM是否可以作为女性不孕症的预测标记.
探索RFM和不孕症风险之间的剂量反应关系.

主要方法:

利用了2017-2020年国家健康和营养检查调查 (NHANES) 的数据.
包括1487名年龄在20-44岁之间的女性参与者.
采用多变量逻辑回归和限制立方 (RCS) 来进行统计分析,并根据年龄,种族和BMI等混因素进行调整.

主要成果:

在RFM和女性不孕症之间发现了显著的积极关联.
每个单位的RFM增加与不孕症风险增加6%相关 (OR=1.06,95%CI=1.01-1.12,P=0.019).
结果在各个子组保持一致,表明强度.

结论:

相对脂肪量 (RFM) 与女性不孕症有显著的关联.
RFM显示出作为一种有价值的不孕症查工具的潜力.
需要进一步的研究来验证RFM在生殖健康评估中的临床适用性.

关键词:

身体脂肪身体脂肪不孕不育不孕不育不孕不育尼汉斯 (NHANES) 是一个名人.相对脂肪质量相对脂肪质量生殖健康生殖健康

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