人工智能在肺癌临床翻译中的进展和挑战
Erjia Zhu1,2, Amgad Muneer2, Jianjun Zhang1
1Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
NPJ precision oncology
|July 2, 2025
概括
人工智能 (AI) 显著提升了肺癌的治疗,帮助戒烟,查和治疗. 解决人工智能偏见对于未来瘤学临床应用至关重要.
科学领域:
- 在瘤学瘤学.
- 医疗信息学 医疗信息学
- 人工智能在医学中的应用
背景情况:
- 人工智能 (AI) 算法正在彻底改变癌症护理.
- 肺癌管理为人工智能集成提供了独特的机会.
研究的目的:
- 审查人工智能在肺癌管理中的变革性影响.
- 讨论AI在临床实践中的障碍和未来方向.
主要方法:
- 审查当前的AI应用在肺癌.
- 分析人工智能算法,如卷积神经网络和变压器.
- 讨论包括模型偏见和公平性在内的挑战.
主要成果:
- 人工智能在戒烟,个性化查和肺癌成像基因组学方面显示出潜力.
- 人工智能可以通过数据集成优化治疗选择.
- 人工智能实施的关键障碍包括偏见和公平性问题.
结论:
- 人工智能有望显著改变肺癌管理.
- 克服像偏见这样的挑战对于成功的临床整合至关重要.
- 未来的研究应该专注于在瘤学中道德和实际的AI部署.
相关概念视频
Targeted Cancer Therapies
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
There are several types of targeted therapies against specific...
Improving Translational Accuracy
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...


