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Updated: Sep 17, 2025

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人类TREX-2和mRNP重塑中的相关复合体对DDX39B调节的结构机制

Bradley P Clarke1, Shengyan Gao2, Menghan Mei1

  • 1Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA.

Nature communications
|July 2, 2025
PubMed
概括

一个新的核复合体,TREX-2.1,从信使核糖核蛋白粒子 (mRNP) 中释放DDX39B (UAP56). 这一发现澄清了DDX39B在mRNP加工和核出口中的功能周期.

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