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Updated: Sep 17, 2025

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由结构研究揭示的在无素受体hRpn13中的一个自适应性结位

Bakar Hassan1, Monika Chandravanshi1, Martin Y Ng2

  • 1Protein Processing Section, Center for Structural Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.

Nature communications
|July 2, 2025
PubMed
概括

在hRpn13中的泛素 (Pru) 域的普雷克斯特林类受体结合了泛素和乱的基质序列. 这种双重结合机制对于基质转移到蛋白酶ATPases至关重要.

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