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Updated: Sep 17, 2025

Visualization of the Axonal Projection Pattern of Embryonic Motor Neurons in Drosophila
11:56

Visualization of the Axonal Projection Pattern of Embryonic Motor Neurons in Drosophila

Published on: June 16, 2017

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SEMA3B将轴突-轴突切换为非髓化轴突包裹和完整性所需的轴突-质相互作用

Li Liu1,2,3, Zhigang Gao4, Xueyuan Niu5

  • 1Department of Neurology of the Second Affiliated Hospital and Department of Human Anatomy, Histology and Embryology, System Medicine Research Center, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, China.

Nature communications
|July 2, 2025
PubMed
概括

在 Schwann 细胞 (SCs) 中的 SEMA3B 信号传递对于分离非髓化轴突 (nmAs) 和促进轴突-质相互作用至关重要. 在神经受伤后恢复SEMA3B有助于nmA重新关联,并减少疼痛.

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相关概念视频

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Nervous Tissue: Myelin

The myelin sheath is a multilayered lipid and protein covering that insulates the axon of a neuron, enhancing the speed of nerve impulse conduction. Axons without this sheath are referred to as unmyelinated. Two types of neuroglia, Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS) are responsible for producing myelin sheaths.
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...
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Action Potential

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A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
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