通过指甲折叠视频毛囊镜检查异常的外周微循环,揭示了冠状动脉心脏病中动脉样硬化的严重程度
Yanan Chen1, Mengmeng Ren1, Chunxiao Wang2
1Department of Cardiology, Yantai Yuhuangding Hospital, Yantai, 264000, Shandong, China.
Scientific reports
|July 2, 2025
概括
外周微血管病,以毛细血管长度减少和血栓增加为特征,在冠状动脉心脏病 (CHD) 患者中存在. 这些微循环变化与心血管疾病的严重程度相关,这表明查的可能性.
科学领域:
- 心血管医学 心血管医学
- 微循环研究 微循环研究
- 诊断生物标志物 诊断生物标志物
背景情况:
- 在各种疾病中观察到外周微血管病变.
- 它在冠心病 (CHD) 中的存在仍然不清楚.
- 研究心血管疾病患者的微循环变化至关重要.
研究的目的:
- 为了确定患有冠心病 (CHD) 的患者是否存在外周微循环变化.
- 评估外周微血管病变与心血管疾病严重程度之间的相关性.
- 探索外周微血管病变作为冠心病潜在生物标志物的实用性.
主要方法:
- 对219名患者进行了指甲折叠视频毛囊镜检查,分为对照组和心血管疾病组.
- 倾向性得分匹配 (1:1比) 用于平衡组特征.
- 对外微血管病变的参数进行了比较,并分析了与心血管疾病严重程度的相关性.
主要成果:
- 与对照人群相比,患有心血管疾病的患者表现出毛细血管长度减少,血栓形成增加以及异常的乳头/亚乳头静脉.
- 心血管疾病的严重程度与毛细血管交叉,血栓形成,乳头异常和整体得分正相关.
- 匹配后的分析证实,心脏病患者的顶端宽度和毛细血管长度减少,心脏病患者的异常和总分数增加.
结论:
- 周围微血管病变在冠状动脉心脏病患者中很明显.
- 微循环变化与心脏病严重程度有显著的相关性.
- 周围微血管病变显示出作为一种用于心血管疾病查和评估的工具的希望.
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