慢性疼痛与吸毒之间存在关联
Rezaul Karim Ripon1, Nasim Maleki2,3
1Harvard T H Chan School of Public Health, Boston, USA.
Scientific reports
|July 2, 2025
概括
慢性疼痛显著增加了物质使用的风险,特别是多种物质的使用. 解决慢性疼痛可能有助于降低物质使用风险.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 疼痛管理 疼痛管理
背景情况:
- 慢性疼痛影响全球数百万人,往往导致有害的应对机制,如物质使用.
- 了解慢性疼痛和物质使用之间的联系对于公共卫生至关重要.
- 以前的研究表明存在潜在的关联,但需要进一步调查.
研究的目的:
- 为了检查慢性疼痛和物质使用之间的关系.
- 为了比较慢性疼痛和没有慢性疼痛的个体中使用物质的几率.
- 确定与单一和多重物质使用相关的与慢性疼痛有关的特定风险.
主要方法:
- 这是一项用国家健康和营养检查研究 (NHANES) 的数据进行的病例对照研究.
- 使用了描述性分析和物流回归模型.
- 分析包括980名个人,根据物质使用状态和疼痛史 (持续或慢性) 进行分类.
主要成果:
- 多重物质使用者表现出明显更高的当前或过去慢性疼痛风险 (aORs 2.28-6.30).
- 单一物质使用者也显示慢性疼痛的风险增加 (aORs 1.19-2.14).
- 与非使用者 (19.33%) 相比,单次 (23.36%) 和多重物质使用者的持续疼痛患病率更高 (39.21%).
结论:
- 慢性疼痛与使用物质,特别是多种物质使用的风险增加密切相关.
- 这些发现强调了对慢性疼痛和物质使用障碍的综合治疗方法的需要.
- 针对慢性疼痛管理的有针对性的干预措施可以作为药物使用的预防策略.
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