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Updated: Sep 17, 2025

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
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在RBMXL1 5'-UTR中的替代拼接诱导了激活B淋巴细胞中的uORF介导的翻译控制

Sylvain de Breyne1, Hélène Polvèche2, Didier Auboeuf3

  • 1CIRI, International Center for Infectiology Research, RNA Expression in Viruses and Eukaryotes (REVE) Team, INSERM U1111, CNRS UMR5308, ENS de Lyon, Université Lyon I, 69007, Lyon, France. sylvain.de.breyne@ens-lyon.fr.

Scientific reports
|July 2, 2025
PubMed
概括

在RBMXL1基因中,一个新发现的替代拼接事件创建了一个小的上游开放阅读框架 (uORF). 这种功能性uORF下调下游蛋白转化,影响细胞中的RBMX/RBMXL1水平.

关键词:
另一个替代拼接方法.B 淋巴细胞激活激活爱斯坦·巴尔病毒病毒.一个RBMXL1翻译法规的翻译法规在 uORF 的情况下.

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