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Updated: May 13, 2026

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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突变和低覆盖全基因组测序识别了前列腺癌血DNA中可操作的DNA修复变化

Alessandra Virga1, Milena Urbini2, Maurizio Polano3

  • 1Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.

Scientific reports
|July 2, 2025
PubMed
概括

使用ctDNA分析的液体活检是识别前列腺癌 (PCa) 患者遗传变化的可靠方法. 将浅层全基因组测序 (sWGS) 与目标分析相结合,可以完善同源重组DNA修复 (HRR) 基因状态的确定.

关键词:
液体活检液体活检低覆盖范围的WGS系统在 PARP 抑制剂.前列腺癌是什么意思 前列腺癌是什么意思

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