怀孕期间基于正念的减压干预改变了母亲的大脑
Yvan Gomez1, Ayako Nakaki2,3,4, Allegra Conti5
1BCNatal Fetal Medicine Research Center (Hospital Clínic and Hospital Sant Joan de Déu), Universitat de Barcelona, Barcelona, Spain.
Scientific reports
|July 2, 2025
概括
怀孕期间以正念为基础的减轻压力对母亲的大脑结构产生了积极的影响,增加了额叶表面积并改变了大脑代谢物. 这种干预在预期母亲身上显示出显著的神经生物学效应.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 放射学 放射学是一门学科.
背景情况:
- 怀孕与显著的神经生物学变化有关.
- 怀孕期间的孕产妇压力会对孕产妇和胎儿的结果产生负面影响.
- 基于正念的压力减轻 (MBSR) 是减轻压力的潜在干预措施.
研究的目的:
- 评估一个为期8周的基于正念的压力减轻 (MBSR) 计划对孕期母亲大脑结构和新陈代谢的影响.
- 分析在MBSR组和通常护理组的孕妇之间皮质形态学和大脑代谢物度的差异.
主要方法:
- 对IMPACT BCN随机临床试验的二次分析.
- 磁共振成像 (MRI) 包括皮质表面积分析和质子磁共振光谱 (1H-MRS) 在妊娠的第三季度.
- 使用五方面正念问卷 (FFMQ) 评估正念.
主要成果:
- 与通常护理组相比,MBSR参与者在右上额头区域的表面积显著增加.
- 1H-MRS显示,在MBSR组中,肌肉内醇度更高.
- 较高的正念分数 (非判断性,非反应性) 与较大的右上额头区域相关.
结论:
- 怀孕期间的MBSR计划显著影响母亲的大脑结构,特别是增加额叶表面积.
- MBSR与母亲大脑代谢物度的变化有关,例如myo-inositol.
- 怀孕期间的正念实践可能会促进母亲大脑的积极神经可塑性.
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