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在Visualize HD研究中,在接受血液透析的中国患者中,高血症的患病率,实践模式和死亡率
Zhao Xinju1, Xing Changying2, Liu Hong3
1Department of Nephrology, Peking University People's Hospital, Unit 10C in Ward Building, 11 Xizhimennan Street, Xicheng District, Beijing, 100044, China.
Scientific reports
|July 2, 2025
概括
超血症 (HK) 影响了40.84%的中国血液透析 (HD) 患者,增加了死亡风险. 在HD中心中,更高的HK患病率与更高的患者死亡率相关,表明需要更好地管理.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床医学 临床医学
- 公共卫生 公共卫生
背景情况:
- 超血症 (HK) 是慢性血液透析 (HD) 患者的常见和严重并发症.
- 了解HD的患病率,风险因素和对死亡率的影响对于改善HD中心患者的治疗结果至关重要.
研究的目的:
- 调查慢性HD的中国患者中HK和相关风险因素的患病率.
- 检查HK在设施水平的流行率和患者死亡率之间的关系.
- 评估目前的血清 (sK) 管理模式和结合药物的使用情况.
主要方法:
- 在Visualize-HD研究中,来自中国231个HD中心的50,983名患者参加了该研究.
- 收集的数据包括患者人口统计数据,血清水平,并发症和三年死亡率.
- 进行了统计分析,以确定HK的风险因素以及患者和设施层面的死亡率的关联.
主要成果:
- 整体HK (sK>5.0 mmol/L) 的患病率为40.84%.
- 三年累积死亡率为21.3%,死亡患者中有36.7%在最后的测试中患有HK.
- 患有高HK患病率的设施显示所有原因和心血管死亡率增加.
- 过血和增加结药物的使用与更高的HK患病率有关.
结论:
- 超血症在中国的疾病中心非常普遍,并与显著的死亡风险有关.
- 患HD发病率较高的HD中心患者死亡率较高.
- 尽管sK控制很重要,但结合剂药物似乎未得到充分利用,这表明需要改进管理策略.
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