随机对照试验:子结膜麻醉持续时间对静脉内注射期间疼痛感知的影响
Jiyeon Kim1, Louis S Han1, Logan Robinson1
1Ophthalmology, Christchurch Hospital, Christchurch, New Zealand.
Clinical & experimental ophthalmology
|July 2, 2025
概括
在下结膜麻醉 (SCA) 后至少等待3分钟内内注射 (IVI) 显著减少疼痛,并增加患者对未来手术的意愿. 这种等待时间平衡了有效的疼痛管理与临床效率.
科学领域:
- 眼科医生 眼科 眼科
- 麻醉学 麻醉学
- 临床试验 临床试验
背景情况:
- 视内注射 (IVI) 是一种常见的眼科手术.
- 使用利多卡因的副结膜麻醉 (SCA) 用于在IVI期间控制疼痛.
- 没有确定SCA和IVI之间的最佳等待时间.
研究的目的:
- 为了确定子结膜麻醉 (SCA) 和静脉内注射 (IVI) 之间的最佳等待时间.
- 为了平衡有效的疼痛缓解与临床效率.
主要方法:
- 单盲随机临床试验涉及240名患者.
- 在SCA后,患者被分配为2,3,4或5分钟的等待时间.
- 主要结局:疼痛程度 (视觉模拟尺度);次要结局:对未来IVI的意愿.
主要成果:
- 平均疼痛得分随着等待时间的延长而降低 (2.27分钟2分钟到0.58分钟5分钟).
- 随着等待时间的增加,患者愿意重复IVI (92%在2分钟到100%在5分钟).
- 在每个间隔观察到的统计学上显著的差异.
结论:
- 在SCA后的更长的等待时间改善了麻醉效果和患者接受IVI的情况.
- 建议至少等待3分钟,提供低疼痛评分 (1.03) 和高患者满意度 (97%).
- 在疼痛和接受方面,最显著的改善是在2到3分钟的等待时间之间.
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