狗中的欧可莱斯博赫米:甲治疗的挑战和对嗅觉能力的影响
Nathan D Mitchell1, Jenna D Balk1, Jake Hughes1
1Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, United States.
Veterinary parasitology
|July 2, 2025
概括
埃莫德普西德/普拉齐昆 (EP) 对鼻子寄生虫Eucoleus boehmi表现出中度的疗效,而莫克西德丁/伊米达克洛普里德 (MI) 和皮兰特尔帕莫酸/费班特尔/普拉齐昆 (PFP) 单独是无效的,但结合起来是非常有效的. 较低的寄生虫卵数与狗的更好的嗅觉功能相关.
科学领域:
- 兽医寄生虫学 兽医寄生虫学
- 狗的健康 狗的健康
- 虫杀虫的有效性 虫杀虫的有效性
背景情况:
- 鼻毛状体Eucoleus boehmi (E. boehmi) 是一个新兴的兽医问题.
- 关于E. boehmi的生命周期,分布和治疗选择的知识有限.
- 了解E. boehmi对狗健康的影响,包括嗅觉功能,至关重要.
研究的目的:
- 评估三种商业虫药物对猎犬中E. boehmi的疗效.
- 评估E. boehmi感染对狗嗅觉能力的影响.
- 为了比较moxidectin/imidacloprid (MI),pyrantel pamoate/febantel/praziquantel (PFP) 和emodepside/praziquantel (EP) 配方的疗效.
主要方法:
- 使用迷你FLOTAC技术进行了便卵数减少试验 (FECRT).
- 三个治疗组接受了MI,PFP或EP,随后接受了组合疗法.
- 使用自然检测任务来评估嗅觉能力.
主要成果:
- 埃莫德普赛德/普拉齐昆 (EP) 显示中等效 (84%FECR在第11天).
- 莫西德克丁/伊米达克洛普里德 (MI) 和皮兰特尔帕莫酸/费班特尔/普拉齐特 (PFP) 单独是无效的 (分别为58%和35%的FECR).
- 结合MI/PFP实现了高效率 (95%FECR),EP (89%FECR) 在第二阶段的治疗中也是如此.
- 在E. boehmi卵数和嗅觉性能之间观察到中度负相关性.
结论:
- EP显示对E. boehmi的适度疗效;MI和PFP需要组合才能获得高疗效.
- 狗的嗅觉功能可能会受到E. boehmi感染的负面影响.
- 需要进一步的研究来探索额外的虫除草剂和E. boehmi对嗅觉的全部影响.
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