用抗VEGF治疗的黄斑瘤中的轴长度和IOL功率稳定性:使用OLCR生物识别的初步研究
Mehmet Omer Kiristioglu1, Selim Doganay2, Gamze Ucan Gunduz2
1Department of Ophthalmology, Bursa Uludag University School of Medicine, Bursa, 16059, Turkey. mokiristioglu@uludag.edu.tr.
BMC ophthalmology
|July 2, 2025
概括
内抗VEGF治疗斑点 (ME) 一般保持稳定的轴长 (AxL) 和眼内透镜 (IOL) 功率. 使用Lenstar的自动生物识别是可靠的,尽管在具有高中央视网膜厚度 (CRT) 的眼睛中可能会发生显著的AXL变化.
科学领域:
- 眼科医生 眼科 眼科
- 生物识别仪表是如何使用的
- 医疗成像医学成像
背景情况:
- 黄斑 (ME) 影响视力,通常用抗VEGF疗法治疗.
- 准确的轴长度 (AxL) 和眼内透镜 (IOL) 功率测量对于折射结果至关重要.
- 在ME治疗期间生物识别的变化可能会影响手术规划和视觉预后.
研究的目的:
- 在接受抗VEGF治疗的斑点 (ME) 患者中评估轴长度 (AxL) 和眼内透镜 (IOL) 功率的稳定性.
- 评估Lenstar生物识别在这个患者队列中测量AxL和IOL功率的可靠性.
- 调查中枢视网膜厚度 (CRT) 变化和生物识别变异性之间的潜在相关性.
主要方法:
- 对32名患者 (64只眼睛) 的观察性研究,因糖尿病视网膜病变或视网膜静脉封闭而导致单侧ME.
- 轴长 (AxL) 和IOL功率在使用Lenstar光学低相干反射计 (OLCR) 生物测量方法测量治疗前和后.
- 对自动,手动调整和CRT校正的轴线测量进行比较;评估观察者之间的一致性和同伴眼睛的稳定性.
主要成果:
- 抗VEGF治疗显著降低了中枢视网膜厚度 (CRT) 的平均值 (p < 0.001).
- 整体平均轴长 (AxL) 和眼镜功率在治疗前和治疗后保持稳定 (p = 0.091对于AxL,p = 0.401对于眼镜功率).
- 在CRT>300μm (p = 0.044) 的眼睛中观察到显著的AxL减少,而自动Lenstar测量显示出高一致性和观察者间一致性.
结论:
- 轴长 (AxL) 和IOL功率测量在ME抗VEGF治疗后通常是稳定的.
- 具有高CRT的眼睛可能会表现出微妙但显著的AXL变化,这表明生物识别可变性的结构值.
- 伦斯塔Lenstar OLCR生物识别在监测ME患者的现实临床实践中显示出可靠性.
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