维生素A及其衍生物在绿眼病中的潜在益处
Xinyue Zhang1,2, Honghao Yang3, Xiaoyu Zhou1
1Aier Glaucoma Institute, Hunan Engineering Research Center for Glaucoma With Artificial Intelligence in Diagnosis and Application of New Materials, Changsha Glaucoma Diagnosis and Treatment Technology Innovation Center, Changsha Aier Eye Hospital, Changsha, Hunan, China.
European journal of medical research
|July 2, 2025
概括
饮食维生素A (VA) 摄入可能会降低玻璃眼风险,可能提供一种主要预防策略. 进一步研究VA的进一步研究.
科学领域:
- 眼科医生 眼科 眼科
- 营养科学 营养科学
- 细胞生物学 细胞生物学
背景情况:
- 维生素A (VA) 对于正常视力至关重要.
- 新出现的证据表明,VA可能有利于玻璃眼患者.
- 玻璃眼是全球不可逆转的失明的主要原因.
研究的目的:
- 审查维生素A及其衍生物在青光眼预防和治疗中的作用.
- 探索VA在眼睛健康中的作用机制.
- 确定VA和玻璃眼的未来研究方向.
主要方法:
- 现有研究的系统审查和元分析.
- 对VA影响的基于机制的研究进行分析.
- 在文献中搜索VA在眼睛表面健康中的作用.
主要成果:
- 有相互矛盾的结果,但元分析表明,饮食中的VA摄入量可能会降低青光眼的风险.
- VA可能会抑制状网和视神经中的氧化应激.
- VA衍生品可以防止眼睛表面受到青光眼药物的损伤.
结论:
- 饮食中的VA摄入量可能是对玻璃眼的可行初级预防策略.
- VA的机制包括抗氧化作用和细胞反应的调制.
- 需要进一步的研究,以充分阐明VA在青光眼的治疗潜力.
相关概念视频
Glaucoma: Overview
782
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
782
Open Angle Glaucoma: Treatment
586
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
586
Angle Closure Glaucoma: Treatment
705
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
705
Photoreceptors and Visual Pathways
6.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.5K


