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Updated: Sep 17, 2025

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq
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从散装,单细胞和空间转录组学的跨组织基因表达相互作用与交叉WGCNA.

Aurora Savino1,2, Raffaele M Iannuzzi3, Lidia Avalle4

  • 1Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, Via Nizza 52, Turin, 10126, Italy. aurora.savino@unito.it.

BMC genomics
|July 2, 2025
PubMed
概括

我们开发了crossWGCNA,这是一种新型的基因共同表达方法,可以公正地识别相互作用的基因. 这种工具有助于理解复杂的生物系统,例如乳腺癌中的肌层-上皮层通信.

关键词:
乳腺癌 乳腺癌 乳腺癌细胞细胞的通信.共同表达网络的共同表达网络.激光捕捉微解剖是指激光捕捉的微解剖.空间转录组学 空间转录组学瘤微环境是一个微环境.

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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