在住院的炎症性肠道疾病中进行常规心理问题查及其对疾病恶化的无进展生存的影响
1Department of Gastroenterology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, No.366 Taihu Lake Road, Fenghuang Street, Gaogang District, Taizhou City, Jiangsu Province, 225300, China.
住院的炎症性肠病 (IBD) 患者的常规心理查显著改善了无进展的生存率和生活质量,减少了12个月的疾病恶化事件.
科学领域:
- 胃肠病学 胃肠病学
- 精神病学是一个精神病学.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 炎症性肠病 (IBD) 需要除了身体症状之外的综合管理.
- 心理困扰在IBD患者中很常见,并且可以影响疾病的过程.
- 住院IBD患者的心理问题常规查尚未广泛研究长期结果.
研究的目的:
- 评估常规心理查对住院IBD患者无进展生存期的影响.
- 在12个月的随访期内评估查对生活质量 (QoL) 和不良事件的影响.
主要方法:
- 一项回顾性队列研究,涉及1265名活跃IBD患者.
- 患者被分为查队列 (n=827) 和控制队列 (n=438) 使用倾向分数匹配.
- 主要终点:病情恶化的无进展生存 (急诊,住院,手术) 在出院后12个月内.
主要成果:
- 查队列表现出明显更高的无进展生存率 (73.2%) 与对照队列 (53.4%) 相比 (OR=2.376,p<0.001).
- 查队列中的患者经历了更高的无进展平均生存期和更高的质量调整寿命年 (QALYs) (p<0.001).
- 由于住院时间较长,在查队列中发现了在医院获得的静脉血栓栓塞和肺炎的风险增加;没有报告严重不良事件.
结论:
- 住院IBD患者的常规心理查与改善无进展生存率和QoL有关.
- 在活跃的IBD患者中,应鼓励对心理问题的查,以积极影响疾病的进展.
- 虽然有益,但潜在的风险,如增加的医院感染,需要在患者管理中考虑.
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