2023年6月至8月,乌干达Kayunga区饮用受污染的河水引起的霍乱疫情,乌干达2023年6月至8月
Adams Kamukama1, Yasiini Nuwamanya2, Edith Namulondo2
1Uganda Public Health Fellowship Program, Uganda National Institute of Public Health, Kampala, Uganda. akamukama@uniph.go.ug.
BMC infectious diseases
|July 2, 2025
概括
乌干达的一次霍乱疫情被用于饮用和家庭用途的受污染的河水所放大. 公共卫生干预措施,包括禁止饮用水和社区教育,成功结束了疫情.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染病传播 传染病传播
背景情况:
- 霍乱是乌干达持续存在的公共卫生问题,每年发生一次.
- 在2023年7月19日,在四名死亡者和Vibrio cholerae的实验室确认后,在Kayunga区宣布了霍乱疫情.
研究的目的:
- 调查该地区霍乱爆发的规模和传播途径.
- 收集证据,为有效的公共卫生干预提供信息.
主要方法:
- 根据症状和实验室结果,确定了可疑和确诊的霍乱病例.
- 在Lusenke村进行了一项环境评估和一项无与伦比的病例控制研究.
- 利用后勤回归来识别与霍乱感染相关的风险因素.
主要成果:
- 确定了78名病例患者,死亡率为13%. 男人和卢森克村受到的影响不成比例.
- 疫情起源于葬礼后,并通过用于饮用和家庭活动的受污染的河水传播.
- 使用未煮熟/未经处理的河水显著增加了霍乱感染的几率 (aOR=4.5用于家庭使用,aOR=17用于饮用和家庭使用).
结论:
- 疫情很可能是由受污染的河水传播的,由葬礼相关活动放大.
- 公共卫生措施,包括禁止使用河水,社区宣传和预防性抗生素,迅速控制了疫情.
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