血清基本元素和中国成年人的肌肉健康:一个基于社区的研究
Hong Ye1, Dongmei Wang1, Siyang Liu1
1Department of Endocrinology and Metabolism, The Eighth Affiliated Hospital, Southern Medical University (The First People's Hospital of Shunde), No.1 of Jiazi Road, Lunjiao, Shunde District, Foshan, Guangdong, 528308, China.
Nutrition & metabolism
|July 2, 2025
概括
高血清铜与较差的肌肉健康有关,而和与中国成年人的更好的肌肉健康有关. 这些关系因年龄和性别而异,强调了元素平衡的重要性.
科学领域:
- 营养生物化学 营养生物化学
- 人类生理学 人类生理学
- 老年学是一门学科.
背景情况:
- 血清基本元素与肌肉健康指标之间的性别和年龄特定关联存在有限的研究.
- 铜 (Cu), (Zn), (Mg) 和 (Ca) 等基本元素在身体功能,包括肌肉健康中起着至关重要的作用.
研究的目的:
- 研究血清Cu,Zn,Mg和Ca与尾骨肌肉质量 (ASM),握力和脂肪与肌肉比率 (FMR) 之间的线性和非线性关系.
- 探索中国成年人之间这些关联的性别和年龄特定差异.
主要方法:
- 利用了来自5389名中国成年人 (≥18岁) 的数据,进行了生物电阻分析 (BIA) 和血清学测试.
- 采用多变量线性回归,限制立方线 (RCS) 分析,子组分析,线性趋势和相互作用测试.
- 根据身体质量指数 (BMI) 调整的ASM和握力进行分析.
主要成果:
- 血清Cu与ASM/BMI和握力/BMI负相关,与FMR正相关.
- 血清Zn与ASM/BMI和握力/BMI正相关,与FMR负相关.
- 血清Cu与年轻人肌肉质量/力量的负相关性更强,与女性肌肉质量/力量的积极相关性更强;观察到Cu/肌肉质量/力量和Zn/握力之间的非线性关系.
结论:
- 血清Cu的升高与肌肉健康的降低有关,年龄和性别影响这些关联.
- 血清中Zn和Ca的增加与改善的肌肉健康有关.
- 保持平衡的血清基本元素对肌肉健康很重要,需要进一步研究.
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