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Updated: Sep 17, 2025

Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta
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Published on: December 5, 2019

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E3 泛基因酶,RNF219,抑制 CNOT6L 的表达,以表现出抗增殖活性

Shou Soeda1,2, Melissa Montrose1, Akinori Takahashi1

  • 1Cell Signal Unit, Okinawa Institute of Science and Technology, Japan.

FEBS open bio
|July 2, 2025
PubMed
概括

环指蛋白219 (RNF219) 通过蛋白质体降解抑制CNOT6L的表达,影响细胞增殖. 低RNF219水平与三阴性乳腺癌预后不佳相关.

关键词:
CCR4-NOT复合体是一个复合体.CNOT6L 其他产品在RNF21919中,癌症 癌症 癌症 癌症 癌症已经死亡的enylation.无处不在的化物化酶

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