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诱导的周周病变的金属学特征-体内研究
Jennifer Santos Pereira1, Brenda Fornazaro Moraes1, Anna Carolina Neves Leutz1
1Division of Endodontics, Department of Restorative Dentistry, Piracicaba Dental School, State University of Campinas (FOP-Unicamp), Piracicaba, SP, Brazil.
International endodontic journal
|July 2, 2025
概括
在老鼠的周周病变改变了膜骨中的必需金属水平. 这项研究比较了金属学概况,揭示了与健康对照组相比,患病骨中的,,,,,铁和度的显著变化.
科学领域:
- 口腔生物学 口腔生物学
- 金属学是一门金属学专业.
- 生物化学 生物化学
背景情况:
- 基本金属对于许多生物过程至关重要.
- 牙周病变,通常是由牙感染引起的,可以影响局部组织平衡.
- 了解周周病变中的金属学变化对于理解疾病发病过程至关重要.
研究的目的:
- 描述和比较Wistar大鼠周周病变和健康的膜骨的金属形状.
- 为了研究诱导的周周损伤对十种必需金属度的影响.
主要方法:
- 在76只老鼠的牙中诱导了周围牙病变,与对照.
- 使用放射学,组织学,微计算机断层扫描 (μ-CT),X射线光显微镜 (μ-XRF),扫描电子显微镜与能量分散光谱学 (SEM/EDS),感应联等离子体光辐射光谱学 (ICP-OES) 和感应联等离子体质谱学 (ICP-MS) 分析的样本.
- 量化十种必需金属:,,,,,铁,,,,铜,和.
主要成果:
- 组织学证实了在周围病变中强烈的炎症和膜吸收.
- μ-CT显示了周周区域体积的显著差异.
- 与对照组相比,ICP-OES和ICP-MS在周周病变中显示了,,,,,铁和的度显著增加.
结论:
- 周周病变会导致膜骨内必需金属度发生显著变化.
- 这些金属学变化表明,矿物质平衡的破坏与周围病理相关.
- 这些发现突出了金属失调在周围疾病的发展和进展中的作用.
相关概念视频
02:37Metallic Solids
Metallic solids such as crystals of copper, aluminum, and iron are formed by metal atoms. The structure of metallic crystals is often described as a uniform distribution of atomic nuclei within a “sea” of delocalized electrons. The atoms within such a metallic solid are held together by a unique force known as metallic bonding that gives rise to many useful and varied bulk properties.
All metallic solids exhibit high thermal and electrical conductivity, metallic luster, and malleability. Many...
All metallic solids exhibit high thermal and electrical conductivity, metallic luster, and malleability. Many...
02:58Properties of Transition Metals
Transition metals are defined as those elements that have partially filled d orbitals. As shown in Figure 1, the d-block elements in groups 3–12 are transition elements. The f-block elements, also called inner transition metals (the lanthanides and actinides), also meet this criterion because the d orbital is partially occupied before the f orbitals.