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Updated: Sep 17, 2025

Author Spotlight: Characterizing DNA Replication of Pathogenic Repeats to Uncover Mechanisms of Replication Fork Stalling and Expansion
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Author Spotlight: Characterizing DNA Replication of Pathogenic Repeats to Uncover Mechanisms of Replication Fork Stalling and Expansion

Published on: September 13, 2024

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镜子的起源在人类基因组中重复

Ryan McGinty1, Alisa Lyskova2, Sergei M Mirkin3

  • 1Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, United States.

Nucleic acids research
|July 2, 2025
PubMed
概括

人类基因组中的长镜DNA重复是由简单的双重重复 (STRs) 产生的. 能够形成H-DNA的特定H-动机STRs被过度代表,这表明H-DNA导致扩张和基因组不稳定.

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