2025年 韩国甲状腺协会 放射性治疗甲状腺功能障碍患者的管理指南
Kyeong Jin Kim1, Eyun Song2, Mijin Kim3
1Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.
Endocrinology and metabolism (Seoul, Korea)
|July 2, 2025
概括
新的指导方针为甲状腺功能障碍患者的放射性 (RAI) 治疗提供了标准化的建议. 这些基于证据的指导方针侧重于最佳剂量,饮食建议和监测,以提高韩国的安全性和疗效.
科学领域:
- 内分泌学 在内分泌学.
- 核医学就是核医学.
- 临床实践指南 临床实践指南
背景情况:
- 甲状腺功能障碍,通常是由格雷夫斯病引起的,涉及过度的甲状腺激素产生.
- 目前的治疗选择包括抗甲状腺药物 (ATD),放射性 (RAI) 治疗和甲状腺切除术.
- 需要对RAI治疗进行标准化的临床建议,以确保安全性,疗效和适当的监测.
研究的目的:
- 制定基于证据的临床建议,用于甲状腺功能障碍症的放射性治疗.
- 为RAI治疗建立标准化的协议,重点关注安全性,疗效和患者监测.
- 为韩国临床医生提供最新的指导,以RAI治疗甲状腺功能障碍.
主要方法:
- 专家共识被用来确定关于RAI治疗的六个关键临床问题.
- 进行了一项系统的文献审查,涵盖了2013年至2022年间发表的研究.
- 对RAI的临床适应症被分为推,可以考虑和不推的组.
主要成果:
- 建议使用10至15mCi的固定RAI剂量.
- 建议在治疗前1周避免含丰富的食物;严格的低饮食是不必要的.
- 抗甲状腺药物 (ATD) 应在RAI前3-7天停止使用,并且可以恢复使用.
- 预防性葡萄糖皮质类药物被推用于轻微的甲状腺眼病.
- 建议在治疗后4-6周对甲状腺功能进行监测,然后每2-3个月进行一次,直到稳定,然后再隔6-12个月.
结论:
- 这些指导方针为甲状腺功能增强症的标准化RAI治疗提供了一个框架.
- 个性化治疗决策应考虑临床特征,并发病症和患者偏好.
- 该指南强调了RAI治疗的最新进展及其在韩国的安全应用.
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