睡眠期间大肌肉群运动的年龄相关变化
Maria P Mogavero1,2, Patrizia Congiu3, Giuseppe Lanza4,5
1Vita-Salute San Raffaele University, Milan, Italy.
Journal of sleep research
|July 2, 2025
概括
睡眠期间的大肌肉群运动 (LMM) 的频率增加,持续时间随着年龄的增长而减少. 老年人在REM睡眠期间表现出更多的LMM,这表明与年龄相关的睡眠不稳定.
科学领域:
- 睡眠医学 睡眠医学
- 神经科学是一个神经科学.
- 人类的衰老 人类的衰老
背景情况:
- 睡眠期间的大肌群运动 (LMM) 是常见的,但它们与年龄相关的变化和与睡眠架构的关系尚未完全理解.
- 了解这些运动对于描述整个生命周期的正常睡眠模式至关重要.
研究的目的:
- 在整个生命周期中调查睡眠期间的大肌群运动 (LMM).
- 为了检查LMM,睡眠结构 (REM和NREM) 和年龄之间的关系.
- 建立不同年龄组LMM的规范性数据.
主要方法:
- 在五个年龄组 (从儿童到老年人) 的141名健康参与者接受了多睡眠学 (PSG).
- 获得LMM,与唤醒相关的LMM (LMMA) 和与唤醒相关的LMM (LMMW) 的得分.
- 统计分析比较了年龄组和睡眠阶段 (REM/NREM) 之间的LMM指数和持续时间.
主要成果:
- 随着年龄的增长,LMM频率 (包括LMMA和LMMW) 显著增加;老年人患病频率最高.
- 年轻人中LMM持续时间较长,老年人中较短.
- 在成人和老年人REM睡眠中,LMM和LMMA更普遍,这表明与年龄相关的睡眠碎片化.
结论:
- 与睡眠相关的LMM表现出明显的与年龄相关的趋势,随着年龄的增长变得越来越频繁,持续时间越来越短.
- 老年人REM睡眠期间LMM增加反映了与年龄相关的睡眠不稳定.
- 该研究提供了LMM的规范性数据,并突出了它们与终身睡眠架构变化的联系.
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