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Updated: Sep 17, 2025

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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Published on: May 13, 2019

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在诱导细胞生长停滞的转录延长相关的RNA处理错误

Saeid Parast, Simai Wang, Marta Iwanaszko

    bioRxiv : the preprint server for biology
    |July 2, 2025
    PubMed
    概括

    像NELF和SPT6这样的转录延长因子调节基因表达和mRNA前处理. 它们的耗尽会导致生长停止,这种增长会被Elongin A (ELOA) 抑制,揭示了与细胞衰老和衰老的新联系.

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