透析患者的脏缩:现实世界的长期结果
Concetta Gangemi1, Alessia Gambaro2, Vittorio Ortalda1
1Division of Nephrology, Department of Medicine, University of Verona, Verona, Italy.
Clinical kidney journal
|July 2, 2025
概括
透皮脏脱皮 (RDN) 改善了透析患者的血压,这些患者有抗性高血压. 这种安全的程序没有对贫血,CKD-MBD或透析耐受性产生负面影响,对这个患者群体显示出有前途.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 干预心脏病学 干预心脏病学
- 高血压管理 高血压管理
背景情况:
- 抗性高血压在接受透析的末期病 (ESKD) 患者中流行.
- 在这个人群中对脏缩 (RDN) 的现有研究是有限的,随访时间很短,重点关注血压 (BP).
- RDN对贫血,慢性病-矿物质和骨疾病 (CKD-MBD) 以及透析耐受性的影响仍然未被探索.
研究的目的:
- 评估透皮损伤 (RDN) 的安全性和有效性,用于透析患者的抗高血压.
- 评估RDN对血压控制,贫血,CKD-MBD和透析耐受性的影响.
- 为了研究在RDN后接受脏移植的患者的结果.
主要方法:
- 对14名透析患者 (7例血液透析,7例腹腔透析) 的回顾性分析,这些患者接受了RDN.
- 随访时间从3个月到84个月不等.
- 评估血压,抗高血压药物计数,贫血和CKD-MBD治疗,以及透析耐受性.
主要成果:
- 系统血压和服用抗高血压药物的数量均显著降低 (分别P=.008和P=.018).
- 在血液透析和腹腔透析患者中,RDN的有效性相似.
- 没有注意到对贫血,CKD-MBD管理或透析耐受性的不良影响. 移植进一步改善了相关患者的血压控制.
结论:
- 透皮脏脱皮似乎对透析患者具有抗性高血压有益,改善血压控制.
- 在这种群体中,RDN是一种安全的程序,而不会加剧常见的并发症,如贫血,CKD-MBD或透析不耐受.
- 在RDN之后的移植导致了血液压力管理的额外改善.
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