功能近红外光谱在患有发育性疾病的儿童中的应用:一篇综述
Jing Wang1, Zhuo Zou1, Haoyu Huang1
1Department of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Kunming, Yunnan, China.
Frontiers in neurology
|July 2, 2025
概括
功能近红外光谱学 (fNIRS) 显示出对诊断儿科发育障碍的前景. 这种非侵入性脑成像技术在自闭症谱系障碍和ADHD等疾病中揭示了明显的血液动力学模式,有助于临床翻译.
科学领域:
- 神经科学是一个神经科学.
- 医疗成像医学成像
- 发育儿科 发育儿科
背景情况:
- 功能近红外光谱 (fNIRS) 是一种便携式,非侵入性脑成像技术,用于测量皮质血液动力学变化.
- fNIRS非常适合儿童群体,因为它具有可移植性和抵抗自然环境中干扰的抵抗力.
- 以前的研究已经在各种儿科神经发育疾病中探索了fNIRS.
研究的目的:
- 综合审查fNIRS在儿童发育障碍中的应用.
- 评估fNIRS在这个领域的临床转化潜力.
- 综合关于与特定发育障碍相关的血液动力学模式的发现.
主要方法:
- 使用预定义的策略进行了系统的文献搜索.
- 在选择相关的fNIRS研究时,采用了包含和排除的标准.
- 专注于脑,自闭症谱系障碍,多动症多动症,早产婴儿情况,HIE和语言障碍的研究被审查.
主要成果:
- 对于特定的发育障碍,确定了明显的血液动力学模式.
- 自闭症谱系障碍 (ASD) 显示不典型的社会大脑网络激活.
- 注意缺陷多动症 (ADHD) 患者表现出前额叶皮层活化减弱.
结论:
- fNIRS可以揭示儿科发育障碍的神经生理基础.
- fNIRS显示出作为这些疾病的诊断生物标志物的潜力.
- 本综述为fNIRS在诊断和管理中的临床应用和途径提供了信息.
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