Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

5.2K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
5.2K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

3.0K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
3.0K
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

67
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
67
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

3.3K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
3.3K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

3.2K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
3.2K
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

11.8K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Development and validation of continuous cardiovascular-kidney-metabolic syndrome severity score (cCKMS-S) complementing CKM staging.

Lipids in health and disease·2026
Same author

Trends in the incidence and prevalence of thyroid dysfunction over 18 years and projections for 2030: the Tehran thyroid study.

Journal of diabetes and metabolic disorders·2026
Same author

Thyroid Hormones and Metabolic Syndrome: A Narrative Review of Findings from 18 Years of Follow-up in Tehran Thyroid Study (TTS).

International journal of endocrinology and metabolism·2026
Same author

Sustained Control of Hyperthyroidism in Graves' Disease: Comparison of Thyroidectomy and Long-Term Antithyroid Treatment.

International journal of endocrinology and metabolism·2026
Same author

Association between trajectories of waist circumference with incidence of type 2 diabetes mellitus, Tehran lipid and glucose study.

Scientific reports·2026
Same author

Medical Treatment of Hyperthyroidism; Efficacy and Safety Considerations.

Archives of Iranian medicine·2026

相关实验视频

Updated: Sep 17, 2025

Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance
14:01

Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance

Published on: July 22, 2011

14.7K

中枢甲状腺激素敏感性和糖尿病前期之间的关联:德黑兰甲状腺研究

Ladan Mehran1, Mohammadjavad Honarvar1, Maryam Tohidi2

  • 1Endocrine Research Center, Research Institute for Endocrine Disorders, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Frontiers in endocrinology
|July 2, 2025
PubMed
概括

甲状腺激素敏感性与糖尿病前期风险有关. 较低的敏感性,由较高的甲状腺激素抵抗指数 (TSHI,TT4RI,PTFQI) 表示,与患糖尿病前期的可能性降低有关.

关键词:
参数性甲状腺反指数基于量子的指数.在糖尿病前期,糖尿病前期.甲状腺功能 甲状腺功能甲状腺激素耐药性 甲状腺激素耐药性甲状腺刺激激素指数指数甲状腺热性甲状腺素耐药性指数

更多相关视频

Electrochemiluminescence Assays for Human Islet Autoantibodies
09:15

Electrochemiluminescence Assays for Human Islet Autoantibodies

Published on: March 23, 2018

15.6K
A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

2.9K

相关实验视频

Last Updated: Sep 17, 2025

Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance
14:01

Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance

Published on: July 22, 2011

14.7K
Electrochemiluminescence Assays for Human Islet Autoantibodies
09:15

Electrochemiluminescence Assays for Human Islet Autoantibodies

Published on: March 23, 2018

15.6K
A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

2.9K

科学领域:

  • 内分泌学 在内分泌学.
  • 代谢健康 代谢健康
  • 甲状腺研究 甲状腺研究

背景情况:

  • 甲状腺激素敏感度指数是代谢健康的新兴标志物.
  • 甲状腺激素敏感性和糖尿病前期之间的关系尚不清楚.
  • 这项研究探讨了基于人口的队列中的甲状腺激素敏感度指数和糖尿病前期之间的关联.

研究的目的:

  • 调查甲状腺激素敏感度指数与糖尿病前期之间的关联.
  • 确定甲状腺激素敏感性是否是糖尿病前期风险的独立预测因素.
  • 在一般人群和euthyroid子组中检查这种关联.

主要方法:

  • 一项以人口为基础的研究包括4356名参与者,不包括患有特定疾病或治疗的参与者.
  • 后勤回归模型用于计算糖尿病前期的几率比率 (OR) 和95%置信区间 (95%CI).
  • 甲状腺激素耐药性指数,包括PTFQI,TSHI和lnTT4RI,被分析为每1SD增加.

主要成果:

  • 在完全调整后,增加的PTFQI与较低的糖尿病前期几率 (OR:0.88;95%CI:0.82-0.94) 有显著的关联.
  • 这种关联在女性,非吸烟者和具有负抗甲状腺过氧化酶抗体的人群中是显著的.
  • 在无甲状腺患者中,增加的PTFQI,TSHI和lnTT4RI与降低糖尿病前期的几率有关,与禁食和挑战后2小时的葡萄糖水平有显著的负相关性.

结论:

  • 对甲状腺激素的较低中心敏感性,反映在增加的TSHI,TT4RI和PTFQI中,与糖尿病前期风险降低有关.
  • 这种关联即使在甲状腺功能正常 (euthyroid) 的个体中也是如此.
  • 甲状腺激素敏感度指数可以作为糖尿病前期风险评估的潜在生物标志物.