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在美国成年人中,身体圆度指数和发年加速之间的关联
Yifei Tan1,2, Ni Zeng2,3, Shiwen Yu2
1Department of Ultrasound, West China Second University Hospital, Sichuan University, Chengdu, China.
身体圆度指数 (BRI) 与表现年龄加速有积极的关联,这表明更高BRI的老化速度更快. 这一发现表明,BRI可以预测生物衰老,并为健康衰老策略提供信息.
科学领域:
- 老年学和衰老研究研究.
- 肥胖和代谢健康 肥胖和代谢健康
- 衰老的生物标志物
背景情况:
- 现象年龄加速,即生物年龄和时间年龄之间的差异,反映了各种因素影响的衰老速度.
- 身体圆度指数 (BRI) 提供了一个精确的肥胖度量,但它与发育加速的联系尚未被探索.
研究的目的:
- 为了研究身体圆度指数 (BRI) 和现象加速之间的关联.
- 确定BRI是否可以作为预测生物衰老速度的指标.
主要方法:
- 利用了美国国家健康和营养检查调查 (NHANES) (2005-2020) 中8,848名美国成年人的数据.
- 计算了所有参与者的BRI,体重指数 (BMI) 和发育加速.
- 采用多变量回归模型来探索BRI和现象加速之间的相关性.
主要成果:
- 在所有BRI四分位数中发现了BRI和phenoage加速之间的显著正相关性.
- 较高的BRI水平与逐渐增加的代加速相关,表明生物衰老速度更快.
- 这种关联在各种子组中保持一致.
结论:
- 身体圆度指数 (BRI) 是现象加速度的重要预测指标.
- BRI可能成为评估生物衰老和开发个性化的健康衰老干预措施的宝贵工具.
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