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Updated: Sep 17, 2025

Efficient Generation of Pancreas/Duodenum Homeobox Protein 1+ Posterior Foregut/Pancreatic Progenitors from hPSCs in Adhesion Cultures
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在胰腺发育过程中,Fbxw7调节N1ICD和Sox9的持续性,以确保适当的细胞系分配和分离

Diana Wichmann Graff1, Emilie Liv Bang-Jensen2, Anuska la Rosa Egeskov-Madsen1

  • 1Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.

Development (Cambridge, England)
|July 2, 2025
PubMed
概括

F-box和WD重复域含有7 (Fbxw7) 蛋白对于小鼠胰腺发育至关重要. 它的缺失破坏了原始细胞分化和器官形态发生,允许持续的Notch信号和Sox9表达.

关键词:
发展发展发展 发展发展Fbxw7w7 在线观看N1ICD是指N1ICD是指N1ICD是指N1ICD的意思.没有口,没有口.胰腺是什么? 胰腺是什么?这就是Sox9x9的意义.

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