混合性鼻炎:在儿童和青少年中被低估的诊断?
I Burla Manhães1, F Y Matsumoto2, D Solé2
1Division of General and Community Pediatrics, Department of Pediatrics, Federal University of São Paulo, São Paulo, Brazil.
European annals of allergy and clinical immunology
|July 2, 2025
概括
混合性鼻炎 (MR) 影响了近一半患有过敏性鼻炎 (AR) 的儿童. 一个新的问卷有助于区分MR,其特点是刺激性触发物和较差的症状控制,从儿科患者的AR.
科学领域:
- 儿科过敏和免疫学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 临床诊断 临床诊断 临床诊断
背景情况:
- 混合性鼻炎 (MR) 呈现出来自过敏原和非特异性刺激物的症状,往往超过单独的过敏性鼻炎 (AR).
- 目前的诊断标准和补充测试对于儿童群体的MR缺乏.
- 这项研究解决了在儿童和青少年中识别MR的临床工具的需求.
研究的目的:
- 提出和验证一个调查问卷,以区分儿科患者的MR和AR.
- 估计儿科专科中心内MR的患病率.
- 确定与MR相关的临床特征.
主要方法:
- 一组8-18岁的AR患者填写了18项鼻刺激物质问卷 (NIQ).
- 在至少8个NIQ项目上,MR被定义为≥5的得分,将患者归类为"高刺激负担".
- 评估了症状控制,过敏敏感化,并发症和室内过敏原暴露.
主要成果:
- 使用NIQ标准确定MR的患病率为42.9% (54/126).
- 主要影响男性和青少年的MR,平均年龄为13岁.
- 与AR患者相比,MR患者报告症状控制较差.
结论:
- 混合性鼻炎是被诊断患有过敏性鼻炎的儿童的显著表型.
- NIQ提供了一个实用的工具来区分MR和AR,有效的门是至少八个积极反应 (得分≥5).
- 识别MR至关重要,因为它与儿科患者的症状控制能力下降有关.
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