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丁脱碳酶抑制减轻了与癌症相关的肌肉衰竭

Aneesha Dasgupta1,2,3, Rebecca E Schmitt1,3, Tatsuyoshi Kono4

  • 1Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.

The Journal of experimental medicine
|July 2, 2025
PubMed
概括

胰岛素和胰岛素脱氧酶 (HDC) 的活性在癌症缓冲症中升高,导致肌肉衰竭. 用α-甲基胺 (FMH) 抑制HDC有效地逆转了老年小鼠的肌肉损失.

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