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Updated: Jun 11, 2026

Endothelial Cell Co-culture Mediates Maturation of Human Embryonic Stem Cell to Pancreatic Insulin Producing Cells in a Directed Differentiation Approach
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来自干细胞的β细胞在小鼠移植后会在代谢上成熟

Eliisa Vähäkangas1,2, Jonna Saarimäki-Vire1, Hossam Montaser1

  • 1Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

Diabetologia
|July 2, 2025
PubMed
概括

干细胞衍生小岛 (SC小岛) 在植入小鼠后在代谢上成熟,改善葡萄糖控制和胰岛素分泌. 这表明SC岛是1型糖尿病治疗的安全选择.

关键词:
贝塔细胞是贝塔细胞.植入植入植入植入植入植入植入植入胰岛素分泌的胰岛素分泌.代谢过程中的代谢.线粒体中的线粒体.干细胞是一种干细胞.

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相关概念视频

Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...