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关于精子发生的空间转录分析

Ndifereke Uboh1, Sean Vargas2, Victoria D Diaz1

  • 1Department of Neuroscience, Developmental and Regenerative Biology, The University of Texas at San Antonio, San Antonio, TX, USA.

Methods in molecular biology (Clifton, N.J.)
|July 2, 2025
PubMed
概括

空间转录学揭示了丸中的细胞变异,克服了传统方法的局限性. 这项研究详细介绍了 Seeker (SlideSeq V2) 的应用,用于在小鼠丸中进行空间基因表达分析.

关键词:
生物信息学是一种生物信息学.在RNA-seqqq.塞拉特·塞拉特是什么意思空间转录组学 空间转录组学组织截面 组织截面

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Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
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