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针对晚年认知障碍和抑郁症的口腔虚弱指标:系统性审查
Vittorio Dibello1,2, Vincenzo Solfrizzi2, Madia Lozupone3
1Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Gustav Mahlerlaan 3004, 1081 LA Amsterdam, The Netherlands.
Age and ageing
|July 2, 2025
概括
口腔虚弱指标,如口腔健康不佳和困难,与认知能力下降和晚年抑郁症 (LLD) 有关. 这一系统性审查强调了影响老年人大脑健康的关键口腔健康因素.
科学领域:
- 老年学和认知科学 认知学和认知科学
- 口腔健康和全身疾病的联系 口腔健康和全身疾病的联系
背景情况:
- 口腔虚弱,以口腔功能下降为特征,与老年人群的认知和身体衰退有关.
- 现有的研究已经探索了一些口腔虚弱指标与晚年认知障碍或抑郁症之间的联系,但不是全面的.
研究的目的:
- 系统地审查和澄清各种口腔虚弱指标对晚年认知障碍的影响.
- 调查口腔虚弱指标和晚年抑郁症 (LLD) 之间的关联.
主要方法:
- 对63项涉及超过5600万受试者的研究进行了系统审查.
- 在四个类别中分析了11个口腔虚弱指标:口腔健康状况,口腔运动技能,/吞/唾液障碍和口腔疼痛.
- 进行了广泛的数据库搜索,由两个独立研究人员进行了研究选择和数据提取.
主要成果:
- 四个特定的口腔虚弱指标 - - 减少剩余的牙,牙周病,困难和吞困难 - - 与认知障碍,轻度认知障碍 (MCI),痴呆和LLD显著相关.
- 口腔健康状况的恶化以及,吞和唾液的障碍与认知能力下降,MCI,痴呆症和LLD有关.
- 口腔运动技能下降与认知障碍相关,而口腔疼痛与LLD特别相关.
结论:
- 口腔虚弱的特定指标在老年人认知障碍的发展和进展中起作用.
- 口腔健康状况和功能是可能导致晚年抑郁症 (LLD) 的关键因素.
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