使用近红外反射光谱测量持续和非侵入性全血红蛋白测量
Stefan F van Wonderen1, Andres Aguirre2, Paul Benni2
1From the Department of Intensive Care, Amsterdam UMC Location University of Amsterdam, Amsterdam, the Netherlands.
Anesthesia and analgesia
|July 2, 2025
概括
一个新的近红外反射光谱 (NIRS) 算法准确地在心脏手术患者中持续且非侵入性地测量总血红蛋白 (tHb),帮助进行输血决策.
科学领域:
- 生物医学工程 生物医学工程
- 医疗器械 医疗器械
- 临床监测 临床监测
背景情况:
- 持续的总血红蛋白 (tHb) 监测在手术期间对输血指导具有临床价值.
- 现有的基于脉冲氧计的设备显示了可变的准确性.
- 一个新的近红外反射光谱 (NIRS) 算法提供了非侵入性的,连续的tHb测量.
研究的目的:
- 评估一个新的基于NIRS的算法,用于连续测量tHb的性能.
- 在心脏手术患者中评估NIRS算法的准确性.
主要方法:
- 对3个临床场所的189名心脏手术患者的数据进行了回顾性分析.
- 连续NIRS衍生的tHb与血液气体tHb测量的比较.
- 使用布兰德-阿尔特曼,MAE,RMSE,四象限一致性和错误网分析的统计分析.
主要成果:
- 偏差为0.08g/dL,精度为1.01g/dL,用于NIRS tHb.
- 平均绝对误差 (MAE) 为0.79g/dL,根平均平方误差 (RMSE) 为1.12g/dL.
- 86.1%的四象限一致性,其中84%的测量是在错误网格的临床上可接受的绿色区域.
结论:
- 基于NIRS的算法在心脏外科手术中提供了准确的THb测量.
- 这项技术显示出指导手术内输血实践的前景.
- 需要进一步的研究来验证其在各种临床环境中的使用.
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