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Updated: Sep 17, 2025

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结核菌分泌的毒性因子Rv1435c/hsr1破坏了宿主snRNP的生物发生

Komal Chauhan1, Dipanwita Datta1, Yogita Kapoor2,3

  • 1Cellular Immunology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India.

Proceedings of the National Academy of Sciences of the United States of America
|July 2, 2025
PubMed
概括

结核菌菌 (Mtb) 使用一种分泌的蛋白质,Rv1435c/hsr1,通过干扰结合体组件来破坏宿主RNA拼接. 这种毒性因子会损害抗菌反应,是结核病的潜在治疗点.

关键词:
通过RNA拼接进行RNA拼接.这是SNRPF的SNRPF.这就是U5 snRNA.拼接一个osomeome.结核病是一种肺结核病.

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