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在密集血液护理期间持续监测葡萄糖的真实准确性:一项前性研究

Marieke Tienstra¹, Riemer A Been², Janneke W de Boer¹

¹Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Diabetes technology & therapeutics

|July 2, 2025

概括

持续血糖监测 (CGM) 对于接受密集血液学治疗的患者来说是可行的,尽管存在一些准确性限制. 这项技术可以帮助管理高血糖,而不会造成有害的胰岛素剂量错误.

科学领域:

内分泌学在内分泌学.
血液学血液学血液学
医疗技术医疗技术医学技术

背景情况:

血液性恶性瘤患者容易患上高血糖症,影响治疗结果.
持续的葡萄糖监测 (CGM) 显示出有希望的毛细血管方法检测高血糖.
在密集的血液学治疗过程中,CGM的准确性仍在调查中.

研究的目的:

为了评估CGM的准确性与毛细血管点治疗 (POC) 葡萄糖测量相比.
评估在接受密集血液学护理的成年患者中CGM的性能.
在仿真抗原受体T细胞治疗,全原干细胞移植 (allo-SCT) 和自身干细胞移植 (auto-SCT) 期间调查CGM的可行性.

主要方法:

一项前性研究,比较了同时进行的CGM和POC葡萄糖测量.
包括60名接受密集血液学治疗的成年患者.
使用平均绝对相对差 (MARD),糖尿病技术协会 (DTS) 错误网格分析和百分比协议的准确性评估.

主要成果:

总体平均绝对相对差异 (MARD) 为21.5%,在治疗类型 (allo-SCT 18.3%,自动SCT 27.1%) 中存在差异.
葡萄糖值在15毫克/分升范围内达到了38.1%,在20毫克/分升范围内达到了51.1%,在30毫克/分升范围内达到了75.1%.
糖尿病技术协会 (DTS) 错误网分析表明临床准确性很好,在A+B区有99.6%的对.

结论:

尽管MARD相对较高,但CGM在密集血液学护理中表现出良好的临床准确性.
在这种患者群体中,使用CGM不太可能导致显著的胰岛素剂量错误.
持续的葡萄糖监测似乎是可行的和安全的管理高血糖在密集的血液学治疗期间.

关键词:

CGM 的准确性不断监测葡萄糖的情况.住院治疗住院治疗免疫学免疫学免疫学

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