在轻度至中度无皮炎中WuSheZhiYang药片的有效性:双盲,随机,安慰剂控制试验的协议
相关实验视频
Updated: Jun 20, 2026

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A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
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Xiangjin Gao1, Yuning Ding1,2, Ruiqi Cai3
1Clinical Research Center, Shanghai Skin Disease Hospital, Shanghai, China.
JMIR research protocols
|July 2, 2025
概括
这项随机对照试验调查了针对阿托皮性皮肤炎 (AD) 的WuSheZhiYang (WSZY) 药片. 传统中医药中的WSZY药片旨在缓解阿尔茨海默病的症状,改善患者的生活质量.
科学领域:
- 皮肤病学 皮肤病学
- 综合医学是一个整体的医学.
- 临床试验 临床试验
背景情况:
- 亚托皮炎 (AD) 是一种普遍的,慢性炎症性皮肤疾病,在全球影响着超过2亿人.
- 武雪志阳 (WSZY) 药片是11种中国草药的混合物,传统上用于皮肤状况.
- 目前,有限的高质量的临床证据支持WSZY药片对AD的疗效.
研究的目的:
- 评估WSZY药片在治疗轻度至中度的亚托皮性皮肤炎中的疗效和安全性.
- 与安慰剂相比,测试WSZY药丸可以显著缓解AD症状的假设.
- 为广泛使用的传统中医药配方提供可靠的临床试验数据.
主要方法:
- 这是一项双盲,随机,安慰剂对照试验,涉及60名轻度至中度AD患者.
- 参与者 (18-65岁) 被随机分配 (2:1) 接受WSZY药片加尿素膏或安慰剂药片加尿素膏4周,随后进行4周的随访.
- 主要结局:从基线到第4周的客观评分无皮炎 (SCORAD) 评分的变化. 二次结果包括,生活质量和复发率.
主要成果:
- 在2024年9月获得伦理审批;在2024年10月完成试验注册.
- 参与者招聘启动于2024年12月,截至2025年6月有30人注册;预计将于2025年12月完成.
- 数据分析计划于2026年1月进行;主要结果预计将在2026年夏季公布.
结论:
- 预计这项试验将提供关键证据,证明WSZY药片对亚托邦性皮炎的治疗潜力.
- 这些发现可能会支持WSZY药片作为阿兹海默症患者的新疗法.
- 成功的结局可能有助于减少与阿托皮性皮肤炎相关的疾病负担.
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