相关实验视频
Updated: Dec 29, 2025

08:51
Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
9.2K
格陵兰人口的多发性硬化症. 一个全国性的队列研究
Nete Munk Nielsen1, Mikael Andersson2, Melinda Magyari3
1Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Focused Research Unit in Neurology, Department of Neurology, Hospital of Southern Jutland, University of Southern Denmark, Aabenraa, Denmark.
Multiple sclerosis and related disorders
|July 2, 2025
概括
多发性硬化症 (MS) 在格陵兰并不像以前想象的那样普遍. 这项研究发现,在格陵兰因纽特人中,多发性硬化很罕见,这挑战了先前的高风险国家主张.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 以前的建模表明,格陵兰的多发性硬化症 (MS) 患病率很高.
- 这与丹麦形成了鲜明对比,丹麦是众所周知的MS高风险国家.
研究的目的:
- 确定1973-2014年格陵兰的多发性硬化症 (MS) 患病率和发病率.
- 分析格陵兰岛按种族分层的MS负担.
主要方法:
- 利用了来自丹麦多发性硬化病注册表的验证数据.
- 计算的标准化发病率 (SIR),比较格陵兰和丹麦的人口.
- 包括来自格陵兰和丹麦国家患者登记册的数据,以提高完整性.
主要成果:
- 2014年,格陵兰的MS患病率为每10万人口中的48.29.
- 从1973年至2014年的发病率为每10万人/年0.97.
- 与丹麦非伊努特人相比,格陵兰伊努特人的MS风险明显较低 (SIR=0.02).
结论:
- 这项研究不支持格陵兰是MS高风险国家的说法.
- 多发性硬化症 (MS) 在格陵兰岛的因纽特人中仍然相对罕见.
相关概念视频
Skin Diseases and Disorders
5.0K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.0K
Skin Cancer
5.6K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.6K
Lysosomal Hydrolases
4.4K
Lysosomes are the site for the degradation of macromolecules and biological polymers released during membrane trafficking events such as secretory, endocytic, autophagic, and phagocytic pathways. The membrane-enclosed area of the lysosome, called the lumen, contains hydrolytic enzymes active in an acidic environment. These acid hydrolases are functional at a pH between 4.5 and 5 and are involved in cellular processes such as cell signaling, energy metabolism, restoration of the plasma membrane,...
4.4K

