导致长期COVID的编码诊断的诱导因素
Adrian Heald1, Richard Williams2, Zarak Khan3
1The School of Medicine and Manchester Academic Health Sciences Centre, Manchester University, UK; Department of Endocrinology and Diabetes, Salford Royal Hospital, Salford, UK.
Public health
|July 2, 2025
概括
处于社会不利地位的个人以及黑人/黑人英国人或混合种族的人面临更高的患长期COVID的风险. 多次COVID-19感染也会显著增加这种风险.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染病研究 传染病研究
背景情况:
- 长期COVID在COVID-19感染后表现出持续的症状.
- 了解风险因素对于有针对性的干预至关重要.
- 以前的研究强调了长期COVID的各种风险概况.
研究的目的:
- 将被诊断为长期COVID的个体的特征与匹配的对照进行比较.
- 为了确定与长期COVID诊断相关的人口和临床因素.
- 分析与风险因素相关的COVID-19感染后的死亡率.
主要方法:
- 追溯观察队列研究 (2020年1月 - 2024年1月).
- 利用了285万个人的人口数据库.
- 根据年龄和性别,匹配了26626例长期COVID病例和133165例对照 (COVID-19阳性,没有长期COVID诊断).
主要成果:
- 在长期COVID组中,伴随性疾病负担更高.
- 与黑人/黑人英国人和混合种族相关的长期COVID风险增加,以及社会劣势 (Townsend指数).
- 长期COVID的风险随着伴随性疾病,COVID-19阳性测试人数的增加而增加,并根据疫苗接种状态进行调节. 在计算社会劣势时,BMI没有独立的影响.
结论:
- 处于社会不利地位的个人以及来自黑人/黑人英国人或混合种族群体的人有长期COVID的风险较高.
- 研究结果支持需要采取公共卫生干预措施,解决长期COVID中的社会经济和种族差异.
- 结果将为未来的流行病准备策略提供信息.
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