基于MXene@gold纳米颗粒的可穿戴电化学口味传感器,用于非侵入性汗水皮质醇检测
Weilong Tu1, Meng Sun1, Tianyi Lu1
1School of Mechanical Engineering, Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, Southeast University, Nanjing, Jiangsu Province, 211189, China.
Biosensors & bioelectronics
|July 2, 2025
概括
这项研究介绍了一种可穿戴传感器,用于在汗水中实时检测皮质醇. MXene/AuNPs 吸食传感器提供了一种非侵入性的方法来监测压力生物标志物.
科学领域:
- 生物医学工程 生物医学工程
- 电化学 电化学 电化学
- 材料科学 材料科学 材料科学
背景情况:
- 慢性压力会对身体和精神健康产生负面影响.
- 对像皮质醇这样的压力生物标志物的实时监测至关重要.
- 需要用于生物标志物检测的非侵入性方法.
研究的目的:
- 开发一种可穿戴的电化学胃口传感器,用于检测人类汗水中的皮质醇.
- 为压力监测创建一个具有成本效益和可扩展的解决方案.
主要方法:
- 使用MXene和金纳米粒子 (Mxene/AuNPs) 修改的丝网打印电极 (SPEs).
- 采用与金纳米颗粒结合的阿普坦,用甲基蓝作为电化学指标.
- 集成一个微流体采样器,以有效和未受污染的汗水收集.
- 使用微分脉冲电压计 (DPV) 评估传感器性能.
主要成果:
- 胃感应器在皮质醇检测方面表现出高的特异性.
- 传感器实现了从0.5到500 ng/ml的广泛检测范围.
- 实现了0.1 ng/ml的低检测极限.
- Mxene/AuNPs增强了电极表面积和体固定.
结论:
- 展示了开发可穿戴传感器用于基于汗水的生物标志物检测的实用策略.
- 拟议的适应传感器为非侵入性实时压力监测提供了一个有希望的方法.
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