超出Sparrow的分辨率限制的微气泡在超分辨率超声波中被隔离,使用相模波
Junseok An1, Naohiro Sugita2, Tadahiko Shinshi2
1Department of Mechanical Engineering, Institute of Science Tokyo, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan.
Physics in medicine and biology
|July 2, 2025
概括
这项研究引入了相模波 (PPW) 以隔离超分辨率超声波 (SR-US) 中的微气泡 (MB). 这种方法可以实现更高的MB度,减少高速SR-US成像的采集时间.
科学领域:
- 医疗成像医学成像
- 声学物理 声学物理
- 生物医学工程 生物医学工程
背景情况:
- 超分辨率超声波 (SR-US) 为增强诊断提供了详细的微血管成像.
- 目前的SR-US方法需要低度的微气泡 (MB),导致长时间的数据采集时间.
- 在更高的MB度下有效的成像对于推进SR-US速度和诊断能力至关重要.
研究的目的:
- 开发和验证一种新的方法来隔离和检测高度的单个微气泡 (MB).
- 通过减少声学数据采集时间,使高速超分辨率超声波 (SR-US) 成为可能.
- 为了提高SR-US成像中MB检测的效率和准确性.
主要方法:
- 利用相模波 (PPW) 精确控制声压,并通过调整其点传播函数 (PSF) 强度来隔离单个MB.
- 利用PPW中的破坏性干扰来实现MB的轴距离歧视,补充横向歧视.
- 结合横向和轴向位置估计,以确定MBs的精确2D坐标,即使距离很近.
主要成果:
- 在波长的25%范围内实现了准确的MB位置估计,超过了Sparrow的分辨率限制.
- 使用重叠的PSF模型,无论MB的近距离或数量如何,改进了平均波长的15%的位置精度.
- 证明能够有效地隔离和检测单个MB,即使在高度.
结论:
- 开发的基于PPW的方法成功地在高度下隔离了个别MB,克服了传统超声波平面波的局限性.
- 这种技术显著减少了声学数据采集时间,为高速SR-US.铺平了道路.
- 增强的MB检测精度有望提高SR-US的诊断精度和临床应用.
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