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机械循环支持的当代结果,在儿童中使用体外连续流动:来自ACTION学习网络的报告

Jiyong Moon¹, Lawrence Greiten², Christina VanderPluym³

¹Division of Cardiovascular and Thoracic Surgery, Dell Children's Medical Center, Austin, Texas.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

|July 2, 2025

概括

在儿童中,机械循环支持与副体持续流量 (pCF) 实现了78%的积极结果. 与非心脏病患者相比,先天性心脏病患者的结果更差,死亡率更高.

科学领域:

儿童心脏病学儿童心脏病学
机械循环支持机械循环支持
遗传性心脏病是一种先天性心脏病.

背景情况:

机械循环支持 (MCS) 对儿科末期心力衰竭至关重要.
准体持续流 (pCF) 在儿科MCS中越来越多地使用.
评估儿童pCF的临床结果是必不可少的.

研究的目的:

评估PCF在儿科患者中的有效性和安全性.
为了比较患有和没有先天性心脏病 (CHD) 的儿童之间的结果.
根据心血管疾病生理学 (单体与双心室) 分析结果.

主要方法:

使用ACTION数据库 (2018年4月 - 2023年7月) 进行的多中心回顾性研究.
包括使用PCF支持的儿童.
主要结局:移植,扩张或持久装置的生存率;次要结局:不良事件.

主要成果:

367名患者 (204名心血管疾病患者,163名非心血管疾病患者) 接受了PCF支持 (中位数为25天).
总体阳性结局为77.9% (存活/持久装置/恢复).
与非心脏病患者相比,心脏病患者的阳性结果较低 (73.0%vs82.2%) 和死亡率较高 (24%vs14.1%).

结论:

在当代队列中,儿童使用pCF与78%的积极结果有关.
患有心血管疾病的儿童在pCF支持下表现较差,死亡率增加.
单心室和双心室冠状动脉疾病的结果相似,但单心室的康复率较低.

关键词:

遗传性心脏病是一种先天性心脏病.机械循环支持机械循环支持副身体的连续流量.儿科儿科儿科腹腔室辅助器件可以帮助心室.

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