月经周期中的通风差异:系统性审查和元分析
Catherine A Rattley1, Paul Ansdell2, Louise Burgess1
1Department of Rehabilitation and Sport Sciences, Faculty of Health and Social Science, Bournemouth University, Bournemouth, UK.
Respiratory physiology & neurobiology
|July 2, 2025
概括
分钟通风 (V·E) 在卵泡阶段低于休息和次最大运动期间的状阶段. 孕激素的变化解释了运动期间的一些VE差异,但在最大强度时,荷尔蒙的影响是最小的.
科学领域:
- 运动生理学 运动生理学
- 生殖内分泌学 生殖内分泌学
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 由于性激素的变化,每分钟通风 (V̇E) 可能在月经周期内波动.
- 这些荷尔蒙变化可能会以运动强度依赖的方式影响VE.
研究的目的:
- 系统地审查和元分析毛囊和状阶段之间的V·E,呼吸频率 (RF) 和潮体积 (VT) 的差异.
- 为了评估这些差异,在休息状态下,在次最大运动 (≤90% V ̇O2max) 和最大运动 (100% V ̇O2max) 期间.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 包括健康的,不使用荷尔蒙避孕药的阴道外流女性.
- 在Cochrane,PubMed和EBSCO中进行的搜索;使用修改后的Downs和Black检查清单进行质量评估.
- 用于分析V̇E,RF和VT的元分析和元回归,强度,持续时间和孕激素变化作为调节者.
主要成果:
- 包括35项研究 (743名参与者,64个数据集).
- 毛囊期的V̇E显著低于静止期的质期 (p<0.001) 和在次最大运动期间 (p<0.001).
- 孕激素的变化显著预测了在亚最大运动 (p=0.02) 期间的V̇E,但不是在休息时 (p=0.07). 观察到对RF和VT的影响很小.
结论:
- 月经周期显著影响V̇E,在卵泡阶段值较低.
- 孕激素部分解释了运动期间的VE变化,但不是在休息时.
- 在最大的运动强度时,对V̇E的荷尔蒙影响是最小的,这表明生理因素占主导地位.
相关概念视频
Hormonal Regulation of the Menstrual Cycle
718
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
718
The Menstrual Cycle
1.4K
The menstrual cycle is a recurrent sequence of changes in the uterine endometrium, specifically its functional layer, the stratum functionalis. This cycle prepares the uterus for potential pregnancy. This cycle typically spans 21–35 days, averaging 28 days, and aligns with the ovarian cycle, regulated by fluctuating levels of ovarian hormones, primarily estrogen and progesterone.
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a...
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a...
1.4K
Factors Affecting Pulmonary Ventilation
1.6K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.6K
Assessment of Ventilation I: Respiratory Rate
1.3K
Assessment of Ventilation
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
1.3K
Assessment of Ventilation II: Respiratory Depth and Rhythm
1.8K
Respiratory Depth
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
1.8K
Physiological Control of Respiration
3.6K
Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
3.6K


