预孕和产前大麻使用与母乳养的关联
Kelly C Young-Wolff1, Sara R Adams2, Kenya J Homsley3
1Division of Research, Kaiser Permanente Northern California, Pleasanton, CA; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, CA; Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, CA.
American journal of preventive medicine
|July 2, 2025
概括
产前大麻使用与更早停止母乳养和在6个月和12个月的更低率有关. 使用大麻对母乳养行为的影响很小.
科学领域:
- 生殖健康 生殖健康
- 母婴健康 母婴健康
- 大麻使用研究 大麻使用研究
背景情况:
- 哺乳是全球推的婴儿养实践之一.
- 孕前和产前大麻使用对母乳养行为的影响仍然不清楚.
- 了解这些关联对于公共卫生指导至关重要.
研究的目的:
- 调查孕前和产前大麻使用以及母乳养行为之间的关系.
- 评估母乳养的持续时间和患病率与怀孕期间大麻暴露的关系.
- 分析大麻使用频率及其对母乳养结果的影响.
主要方法:
- 一项基于人口的回顾性队列研究,涉及北加州200,207例怀孕 (2016-2022年).
- 在怀孕早期对大麻使用的查,将暴露分为产前使用,仅使用或不使用.
- 使用健康儿童访问数据和统计建模 (修改的Poisson和Cox回归) 对母乳养开始,持续时间和排他性的纵向评估.
主要成果:
- 在所有组中都观察到高的母乳养率 (总体为94.6%).
- 产前大麻使用与更早停止母乳养 (aHR 1.12) 和6个月 (aPR 0.84) 和12个月 (aPR 0.81) 的较低患病率有关.
- 与产前大麻使用频率增加的关联更为强烈;怀孕前使用显示出最小的差异.
结论:
- 产前大麻暴露与母乳养时间缩短和持续母乳养率降低有关.
- 高的母乳养开始并不排除产前大麻使用对母乳养的负面影响.
- 对于使用大麻的孕妇,可能需要进一步的研究和有针对性的干预措施.
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