与2021年至2023年之间Butembo心力衰竭严重程度和死亡率相关的因素
Jean-Paul Paluku Mwalitsa1, Jean-Paulin Mbo Mukongole2, Zacharie Tsongo Kibendelwa2
1Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo.
Current problems in cardiology
|July 2, 2025
概括
在刚果民主共和国东部,本土的抗毒品和风湿性膜心脏病显著加重了心力衰竭的结果,增加了死亡率. 解决这些因素对于改善患者的生存率和生活质量至关重要.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 热带医学 热带医学
背景情况:
- 心力衰竭是一个重大的全球健康挑战,其特点是患病率和死亡率高.
- 区域因素对心力衰竭的患病率和结果产生重大影响,需要本地化管理策略.
研究的目的:
- 确定影响心力衰竭患者生活质量和生存的关键因素. 刚果民主共和国东部.
- 根据刚果民主共和国东部的特定环境,制定了针对心力衰竭管理方案.
主要方法:
- 在2022年1月至2023年12月期间进行了一项描述性分析研究.
- 156名心力衰竭患者 (平均年龄62±15岁) 被纳入研究,并进行了12个月的随访.
- 数据分析的重点是将患者的特征和治疗与临床结果相关联.
主要成果:
- 在心脏病患者中,心力衰竭的频率为17.5%. 严重程度与本地抗毒品产品的使用和膜心脏病 (p<0.000) 有关.
- 死亡率与本地抗毒品产品使用 (41.2%),糖尿病持续时间 (>5年:33.3%),扩张性心肌病 (18.9%) 和膜心脏病 (17.5%) 有显著关联.
- 根据心力衰竭表型 (HFrEF 30.9%) 和严重程度 (NYHA IV 55.6%) 的死亡率有所不同.
结论:
- 本土抗毒品的使用和风湿性膜心脏病是该地区心力衰竭恶化和过早死亡的主要原因.
- 针对这些具体因素,有可能改善刚果民主共和国东部心力衰竭患者的存活率.
- 对本土产品毒性和风湿性心脏病患病率的机制进行进一步研究是有必要的.
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