对Zwitterionic表面活性剂 (Sulfobetaine 10) 与聚合易感蛋白的相互作用的生物物理见解

Abdulaziz Alamri1, Ajamaluddin Malik1, Javed Masood Khan2

  • 1Department of Biochemistry, College of Science, King Saud University.

PubMed
概括

硫贝-10 (SB10) 防止蛋白质聚合并保持溶解性,为神经退行性疾病提供潜在的治疗益处. 然而,SB10并不能促进蛋白质的重新折叠,这表明静电相互作用的重要性.

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